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8 Alternatives Compared

When TMS isn't
the answer.

TMS isn't the only option. Compare other evidence-based treatments for depression, PTSD, OCD, and treatment-resistant conditions.

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8
Treatments
3
FDA-Cleared
5
Emerging

See how TMS therapy works for your condition.

FDA-Cleared Alternatives

Treatments with regulatory approval and broad insurance coverage.

FDA Cleared

Spravato (Esketamine) Nasal Spray

FDA-cleared nasal spray for treatment-resistant depression. Administered in-office with 2-hour monitoring. <a href="/treatments/depression/" style="color:var(--accent); text-decoration:underline;">Learn how TMS compares</a>.

Onset
Hours-Days
FDA Cleared

Electroconvulsive Therapy (ECT)

Gold standard for severe, life-threatening depression. Requires anesthesia. Highest remission rates of any treatment. <a href="/treatments/depression/" style="color:var(--accent); text-decoration:underline;">Learn how TMS compares</a>.

Onset
Days-Weeks
FDA Cleared

Vagus Nerve Stimulation (VNS)

Surgically implanted device stimulating the vagus nerve. For severe treatment-resistant depression. <a href="/treatments/depression/" style="color:var(--accent); text-decoration:underline;">Learn how TMS compares</a>.

Onset
Months

Emerging & Off-Label

Active research and off-label applications with growing evidence.

Off-label

Ketamine Infusion Therapy

IV ketamine for rapid depression relief. Off-label but growing rapidly. Works within hours. <a href="/treatments/depression/" style="color:var(--accent); text-decoration:underline;">Learn how TMS compares</a>.

Onset Hours
Not FDA Cleared

Neurofeedback Therapy

Brain training using real-time EEG. Teaches self-regulation of brain activity. Non-invasive. <a href="/treatments/depression/" style="color:var(--accent); text-decoration:underline;">Learn how TMS compares</a>.

Onset Weeks-Months
Investigational

Psilocybin-Assisted Therapy

Psychedelic-assisted therapy showing breakthrough results in clinical trials. Not yet FDA-approved. <a href="/treatments/depression/" style="color:var(--accent); text-decoration:underline;">Learn how TMS compares</a>.

Onset 1-2 Sessions
Investigational

Deep Brain Stimulation (DBS)

Surgically implanted electrodes in specific brain regions. Last-resort for the most severe cases. <a href="/treatments/depression/" style="color:var(--accent); text-decoration:underline;">Learn how TMS compares</a>.

Onset Weeks-Months
Off-label

Stellate Ganglion Block (SGB)

Anesthetic injection near the neck targeting PTSD symptoms. Rapid relief, growing evidence base. <a href="/treatments/ptsd/" style="color:var(--accent); text-decoration:underline;">Learn how TMS compares</a>.

Onset Hours-Days

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